Organocatalytic asymmetric Michael addition of 1-acetylcyclohexene and 1-acetylcyclopentene to nitroolefins.
نویسندگان
چکیده
Enantioselective organocatalytic Michael addition reactions of 1-acetylcyclohexene, 1-acetylcyclopentene and 1-acetylcyclobutene to nitroolefins have been developed. This is the first report where an α-branched enone has been activated by an amine catalyst for the asymmetric Michael addition reaction to an electrophile. The Michael products have also been cyclized to bicyclic compounds.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 25 شماره
صفحات -
تاریخ انتشار 2015